Vitamin B12 and protein metabolism.

Fat in the diet of rats. 8 39 carbon dioxide plus soya-bean oil (ratio 2: I) grew poorly, and all died during the first half of the experimental period. 4. The animals fed on a mixture of PT 006 or PT 006 plus distillate-soya-bean oil (ratio 2: I ) grew throughout the whole experimental period (36 weeks), although significantly more slowly than the controls. No neoplastic tissue was found at autopsy. Histological examination revealed pathological changes in the kidneys (abundance of calculi, hyaline casts, uncalcified degenerations of the tubules and necrosis of the papilla), liver (degeneration of the central zone of lobules) and the small intestine (hyperplastic chronic enteritis).